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Meldonium

Full Guide on Mildronate regarding cost, dosage and places to buy it online

 

The complete information regarding what mildronate is, what is its cost, recommended dose and where to buy it online is provided in detail below.

Other names: Meldonium, Mildronāts also known as Quaterine, MET-88 and THP

Meldonium

This is an anti-ischemic drug came to attention of world when Maria Sharapova, five-time grand slam champion and world’s number one tennis player confessed that she had failed a drug test at the Australian Open in January. She was found positive for this medication. She was taking the substance to enhance her athletic performance for last 10 years but it was banned only this same year.

Where can I buy Mildronate?

Online pharmacies is the best place to buy this medication. It is available on various websites but one should purchase it only from the reliable online sites. Renowned and reputed online platforms ensure the precise quality and quantity and deliver it in air-tight and sealed packaging. The manufacture and expiration date are also given on the product.

Cost of Meldonium:

The cost of the drug varies at various online pharmacies. It comes in the form of capsules. A retail box containing 60 pills may be purchased for $49.99. The price may vary from $49.99 to $58.95 for a package of 60 capsules on different sites. The quantity of pills and packs deduce the actual cost. It is also available to buy online in different packaging of 180 pill 3-packs for $139.99, pack of 40 capsules for $39.99 and so on. The cost varies with the place you buy it from. See below:

Meldonium 500 mg pricelist

Meldonium 500 mg pricelist

 

Meldonium 250 mg pricelist

Meldonium 250 mg pricelist


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What is Mildronate?

It is an anti-ischemic-drug used-clinically to treat-angina, myocardial infarction, chronic heart failures and improvising circulation, particularly in the brain. It is manufactured-in Latvia and is also known as ‘Meldonium’. It is effective for treatment of heart ischemia and its consequences. It is also revealed to have effects on cerebral circulation disorders and central nervous system functions. Neurological clinics use it in treating patients of brain circulation disorders. Mildronate (aka Mildronat, Mildonium) is a nootropic, vasodilator and CNS stimulant that unravels the strong logical and physical prospective.

 Proper dosage and intake recommendation:

Maximum daily intake of the dose must not exceed 2000 mg i.e. 4 tablets a day. For beginners, it is recommended to start with one 500 mg tablet each morning. They can slowly increase this dosage to two, three and finally four tablets a day. Do not take medicine if there is 8 hours of planned bedtime ahead.

The suggested dose in special cases is mentioned below:-

– Cerebral Circulation Disorders: These patients need to take one capsule of 500 mg daily. Duration of the therapy is 4-6 weeks.
– Physical and Intellectual Stress: Take half pills four times a day. Duration for its continuation is only 10-14 days.
– Athletic Performance of Sportsmen: The advised dose for refining the athletic performance of the body is 1-2 capsules twice daily. It should be taken 40-60 minutes before workouts. Duration of therapy in the preparatory training is 2-3 weeks. And when undergoing any competition, reduce it to 10-14 days.
– Alcoholism: One pill should be taken four times a day to recover from chronic alcoholism. Period of therapy is 7-10 days.

Note: The product is not FDA evaluated and should only be considered for use after consulting to a registered physician.

Working of Mildronate:

Latvian Institute of Organic Synthesis developed Mildronate to deter carnitine biosynthesis. Carnitine is a chief controller of fat metabolism. It transports the fatty acids into mitochondria for a fatty acid breakdown. Meldonium prevents this amassing of cytotoxic byproducts of fatty acid beta-oxidation in ischemic tissues. It protects-mitochondria from an excess of fatty acid metabolisms. This is a highly oxygen-consuming process that must be blocked. And this therapy reduces the beta-oxidation-of fatty acids by shifting it towards the-oxidation of carbohydrates. This consumes very less oxygen per-ATP molecule than the previous mechanism.
The structural-analogue of the drug is based on the gamma-butyrobetaine. This substance is found in the human cells. The medicine reinstates the balance of necessary oxygen supply to the cells by eliminating the gathered toxic metabolic products and safeguarding them from any harm. The revitalizing stimulant effect of the drug boosts the consumption of oxygen by muscle and brain cells. Effect of the Mildronate in the cell:

 

– Meldonium escalates the mental processes like learning, processing and concentrating.
– It lessens the fatigue and enriches the alertness and motivating power.
– Remarkable in catalyzing the overall athletic and competitive performance.
– The boosted oxygen delivery causes improvement in the process of microcirculation.

Side-effects of the medication:

Meldonium is a well-tolerated medicine. Slight side-effects after consuming it may occur. If there is a symptom of allergy then consult a doctor before continuing it. The minor side-effects when under the therapy are: –

  • Itching, accelerated heartbeat, dyspepsia or excitement is possible in certain cases.
  • Digestive disorders like nausea and vomiting.
  • Changes arterial pressure towards hypotension.
  • In allergic reactions, it can cause redness, rash and swelling.

Pros and Cons of the usage:

The treatment has several advantages and disadvantages. The advantages are far better and an added point to its usage.

The main Pro is:

– It enhances the huge supply of oxygen to the cells in muscles and brain. This is the most significant benefit of the usage.

Other pros of the pill are:

  • It drops the lactate level and urea-in blood.
  • Upsurges physical working competencies.
  • Boosts the rate of recovery-after maximal and sub-maximal-loads.
  • Increases the property of enduring.
  • Improves the glycogen level in the cells.
  • Advances the functioning of the heart.
  • Activates functioning of the CNS and protects-against stress.

Disadvantages:-

The treatment has almost no harm when taken in the prescribed manner.

  • It can adversely affect if the intake quantity is amplified than suggested. Minors have to remain watchful while consuming it. The exceeded quantity and age factor are the disadvantages of this pill.
  • Patients with chronic liver diseases and kidney failures must carefully consume the drug for long time.
  • Do not consume when suffering from Acute Coronary Syndrome.
  • Children and adolescents under the age of 18 can take it only with a proper doctor prescription.

 

Summary

Mildronate allows the body to better utilize its natural resources for producing more energy. It treats the diseases related to heart and brain. Athletes can use Meldonium for coping up with physical labor. It can be used by students and intellectuals for improving the mental capability. The unique mode of action with negligible side-effects make the drug a decent supplement for people with mental and physical overload. It is available to buy online for around $49.99 per pack of 60 capsules and is fuss-free to purchase. The recommended dosage of 2000 mg daily increases the resistance power of the body to adverse circumstances.

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